Introduction

In this article I’ll describe how to lose weight fast and briefly about weight loss chemistry. Also, there is information about different types of weight loss drugs and what is it.

Metabolism

There are two parallel processes in an organism always: lipolysis and glycolysis. Lipolysis is the metabolic process of breaking down fats into their constituent fatty acids under the action of lipase. Glycolysis is the process of glucose oxidation, when two pyruvic acid molecules are formed from one glucose molecule. Glycolysis consists of a sequential chain enzymatic reactions and is accompanied by energy storage in the form of ATP and NADH. Glycolysis is a universal pathway of glucose catabolism and one of the three (along with the pentose-phosphate pathway and the Entner-Dudorov pathway) pathways of glucose oxidation found in living cells.

The main rule of weight loss is caloric deficit. This is the basis of fat reduction in an organism. The weight loss is a complex process which includes increasing of physical activity and dieting. To improve the metabolism, the external stimulation has to be done sometimes. The mentioned goal can be achieved by medical drugs intake.

It is essential to remember that even the best weight loss remedy could be dangerous to people’s health. It has to be consulted a doctor to exclude possible risks.

Weight loss drugs

Weight loss drugs are classified by action principles:

1. Anoretics suppress appetite sibutramine, a substance that sends satiety signals to the brain.

• Adrenalin anorectics: phentermine, mazindol. Impact on the CNS and suppress the hunger center in the brain. Have addicted effect.
• Serotonin anorectics: fluoxetine, fluvoxamine, etc. Serotonin drugs suppress appetite, increase the effect of serotonin in the brain, participate in impulse transmission in the CNS, and can regulate sleep. Also decrease fatty and sugary food demand.
• Sport anorectics: testoripped, colonoxy, adipozin, lipovox, rimonabant.
• Garcinia extract is an appetite suppressant. The mechanism of this effect is not explained. It has been suggested that garcinia may affect the serotonin production, which among other things regulates appetite.

The supplement blocks the activity of fats in the blood and suppresses the new fatty acids production, thus reducing the amount of subcutaneous fat. Garcinia extract has the desired effect only if a person is really overweight and/or stressed. Otherwise, the result is not statistically significant.

2. Fat Burners can be divided into two categories: those ones which accelerate fat metabolism and those ones which decrease the carbohydrates digestibility. Serves for a speeding up metabolic process.

Lipotropics block the fat production by the liver to break down the existing fat deposits.

• Ephedrine activates the metabolism and reduce appetite;
• Caffeine is a psychomotor stimulant. Reduces appetite and activates nervous system. Cons: reduces physical activity.
• Bromelain is a pineapple extract, which has long been known as an effective supplement for women fat burners. The substance has no side effects and is not harmful to the organism. Bromelain speeds up the metabolism, helps digest proteins, breaks down food after intake and removes fat deposits in
• Guarana is made from natural caffeine. It is characterized by a long period of elimination from the body, which has a positive effect on energy levels. The substance stimulates the nervous system, but does not provoke its overexcitation;
• Fat-burning supplements: taurine and glycine. Its action is based on stimulation of the bile production, which breaks down fats into carbohydrates, acid and water, after that they are quickly eliminated from the body;
• Hormonal drugs: L-thyrexin and similar in their effects. They affect the thyroid gland, change the hormonal background and provide stabilization of metabolic processes. But taking hormonal drugs without a doctor’s control leads to negative and irreversible consequences.

Thermogenics increase the body temperature. The temperature increasing by 0.5-2 degrees launches fat burning processes. Such types of fat burners significantly increase endurance.

• Synephrine is found in oranges. The substance does an excellent job of breaking down fatty acids, reduces appetite and starts metabolic processes;
• Anhydrous caffeine is obtained from tea, coffee fruits, guarana. The substance activates the cardiovascular system, the central nervous system, and activates the fat burning process;
• Green tea extract has antioxidant properties and boosts metabolism;
• Golden root extract is an adaptogen that increases stamina and activates protein metabolism;
• Pepper extract improves protein digestibility and activates protein processes;
• Chromium picolinate is derived from the tryptophan amino acid. The substance increases strength and reduces fatty deposits in the body;
• Guggulsterones, the main element contained in the resin of the Commiphora mukul tree, the juice of the plant is also used. Guggul stimulates the thyroid functioning and reduces the body weight by the hormonal background normalization.

3. Laxatives contribute to the rapid removal of digested food masses. They also make it possible to take out the toxins from a body.

• Polyethylene glycol (MiraLax and generics);
• Stimulant laxatives: Bisacodyl (Dulcolax and generics);
• Magnesium-based laxatives: magnesium hydroxide, magnesium citrate;
• Stool softeners (Colace, Phillips’ Stool Softener and generics);
• Suppository laxatives (Fleet Glycerin Suppository and Dulcolax Medicated Laxative Suppository).

4. Diuretics eliminate excess fluid, getting rid of edema.

5. Developed on the basis of MCC. Microcrystalline cellulose swells out when entering the stomach. This property helps to eliminate sense of hunger.